After easing past Montrose 7-0, Rangers will host a Spartans side who trounced Kilmarnock 6-0.
Last year’s finalists Hearts are rewarded for trouncing Falkirk 9-0 with the opportunity to welcome 9 time winners Glasgow City. City edged past Celtic 3-2 at the weekend.
SWPL 2’s Boroughmuir Thistle will take on Motherwell after earning a well deserved victory of Premiership side Dundee United. Motherwell meanwhile made light work of Bonyrigg Rose with a 6-0 thumping.
In the fourth and final clash will see Aberdeen, 3-0 victors against Hamilton Accies travel to St Johnstone, themselves coming out 4-2 winners to knock out Elgin City.
The games will all be played on the 9th of March.